Doctorate
Doctorate Title: How do changes in blood glucose levels during the nebulisation of salbutamol impact on objectively measured health outcomes in patients presenting with an exacerbation of asthma.
Doctorate Description: Asthma and diabetes are two of the most prevalent long-term conditions worldwide and although seemingly unrelated the commonality of shared comorbidities and potential predisposition for those patients suffering from one of these conditions to develop the other, brings with it intricacies that are often difficult to manage clinically.
One such complexity is around how medications designed to benefit asthmatics could potentially cause changes in patients' blood glucose levels, resulting in a transient diabetic state that adversely affects the patient by worsening/prolonging their exacerbation.
This study seeks to ascertain how beta-2 agonists (salbutamol) used to manage asthma exacerbations in the ambulance setting affect blood glucose levels, and how any changes impact their ventilation (V) and cardiac output (Q).
Details:
Type: PhD
University: Kingston University London
Primary Supervisor: Dr Dimitra Nikoletou
Category: Cardiology & Respiratory
Funding:
Start Date: 2020
End Date: 2026
Status: Ongoing
Thesis
Awaiting
Research Interests
Asthma, Allergy, Paramedicine, Healthcare Education
Publications
Mortimer, C. (2019). A preliminary study to determine the effects of nebulised salbutamol on blood glucose levels during an acute asthma exacerbation. European Respiratory Journal, 54: Conference Suppl. 63, PA4243. https://doi.org/10.1183/13993003.congress-2019.PA4243